Antidepressants Not Working? Ketamine for Depression in New York

Ketamine offers a safe, fast-acting alternative that can shift mood, thought patterns, and emotional presence in days, not weeks.

  • 1–4 Hrs

    First Mood Shift For Many Patients

  • 6 Infusions

    Over 2 To 3 Weeks

  • RN‑Monitored

    Every Infusion, Start To Finish

  • From $550

    $200 Less Than Many NY Clinics

Understanding Treatment- Resistant Depression

Depression affects over 17 million adults in the U.S., but for many, traditional medications don’t work.

After 3-4 failed medications, most
patients begin to feel hopeless,
numb, or disconnected from
themselves.

Ketamine Offers Another Path

1

You try an antidepressant.

2

You wait 6–12 weeks.

3

It doesn’t work–or only helps a little.

4

Your doctor switches medications.

5

You wait another 6–12 weeks.

6

Side effects get worse.

7

You’re told to “try one more.”

1

You try an antidepressant.

""

2

You wait 6–12 weeks.

""

3

It doesn’t work — or only helps a little.

""

4

Your doctor switches medications.

""

5

You wait another 6–12 weeks.

""

6

Side effects get worse.

""

7

You’re told to “try one more.”

""

After 3-4 failed medications, most
patients begin to feel hopeless,
numb, or disconnected from
themselves.

Ketamine Offers Another Path

Is IV Ketamine Right For You?

  • A Good Fit If You

    • Tried 2+ Antidepressants Without Relief
    • Live With Treatment-Resistant Depression
    • Had Tough Side Effects From Medications
  • Not Recommended With

    • Psychosis Or Active Schizophrenia
    • Uncontrolled High Blood Pressure
    • Active Substance Use Disorder
    • Certain Heart Conditions

Dr. Pervaiz Qureshi, MD Depending on circumstances. Dr. Qureshi confirms fit at your consultation.

Why Ketamine Helps When Antidepressants Don’t

Ketamine infusion therapy in New York works differently from SSRIs and SNRIs. Instead of slowly adjusting neurotransmitters like serotonin, ketamine acts on the brain’s glutamate system.

  • Restores Glutamate

    Strengthens synaptic connections responsible for mood and emotional resilience.

  • Rapidly reduces rumination

    Many patients describe it as “quieting” the critical internal voice.

  • Improves emotional presence

    Patients feel more like themselves again, not numb or flat.

  • Works within hours, not weeks

    Many patients notice a first mood shift within 1 to 4 hours.

Symptoms Ketamine Can Help Improve

Even if you’ve had multiple failed antidepressants, ketamine may still be effective.

IV Ketamine, Spravato, or At‑Home Ketamine?

  • Our treatment

    IV Ketamine

    • Full dose reaches your bloodstream
    • Physician-dosed, nurse-monitored
    • Cash-pay with superbill
  • Spravato Nasal Spray

    • FDA-approved for treatment-resistant depression
    • 2-hour observation in clinic
    • Often insurance-covered (not offered here)
  • At-Home Ketamine

    • Lozenges or tablets
    • Only part of the dose absorbed
    • No in-person monitoring

Want insurance coverage first? Ask your insurer about Spravato. Want physician-dosed, fully monitored care? That’s all we do.

What the Research Says

Clinically Studied Outcomes Showing Real-World Improvement

Your Depression Treatment Protocol

Initial Consultation

Medical review, mental health history, symptoms, and treatment planning.

6-Infusion Series

Two infusions per week for 3 weeks (evidence-based protocol).

Optional Integration Therapy

Referrals to trusted integration therapists.

Booster Treatments

Periodic boosters help maintain improvement.

First visit takes about 2 hours. Please arrange a ride home.

Safety & Monitoring

Our medical team is led by Dr. Pervaiz Qureshi,MD. A registered nurse
monitors you throughout every infusion.

Continuous RN monitoring

Dedicated nurse present throughout your entire session

Vital signs tracking

We check BP, heart rate, oxygenation

Precision IV dosing

Carefully calibrated doses for optimal results

Onsite provider

Medical provider present during entire session

Calm environment

Calm, supportive treatment environment

Pricing for IV Ketamine Depression Treatment

  • Same price at both clinics · Cash-pay · HSA/FSA accepted
  • Itemized superbill for out-of-network claims (20 to 50% commonly reimbursed)
  • We don’t bill Medicaid, Medicare, or insurers directly

Where We Treat Depression in New York

  • Long Island (Great Neck)

    By Appointment
    • 45 Middle Neck Rd, Suite #22A  Great Neck, NY 11021
      Open 7 days
    • (516) 445-7191
    • Serving Nassau County, Western Long Island, and Eastern Queens.
    See the Long Island Clinic
  • Queens (Jackson Heights)

    Open 7 Days
    • 37-20 76th St, Suite #100  Jackson Heights, NY 11372
    • (516) 203-1041
    • Serving Queens, Manhattan, Brooklyn, and the Bronx.
    See the Queens Clinic

Same protocol, same price, same medical team. Open 7 days.

What A Patient Says

I struggled with depression, anxiety, and PTSD for years. I’d tried CBT, DBT, EMDR, Lithium, Abilify, and more before finding relief here. Since starting ketamine, I feel so much better, the pain in my body eased, and I feel more positive and safe. That’s a huge success for me.

Ivonne F., Google review

Frequently Asked Questions

How quickly will I feel relief?
Many patients notice a first mood shift within 1 to 4 hours. Improvement usually builds across the six sessions.
Yes. That’s who it’s studied for: Up to 70% of treatment-resistant patients see meaningful improvement, though not everyone responds.
In a medical setting, the risk of dependence is considered very low. Every dose is given in our clinic under nurse monitoring, and nothing goes home with you.
If you’re in danger right now, call 988 or 911. Research shows IV ketamine can reduce suicidal thoughts quickly for some patients. Tell us at your consultation so we can plan your care safely.
Usually, no. Some medications, like high-dose benzodiazepines, can affect ketamine, so Dr. Qureshi reviews every medication first. Some patients later reduce medications with their prescriber.
Most patients find it deeply relaxing and slightly dreamlike. Your nurse monitors you the whole time.

Many patients stay better for weeks to months after the series, with optional boosters every 4 to 8 weeks.

We’ll know within your six sessions, not months. We adjust your plan or discuss alternatives openly.
IV ketamine is cash-pay. We provide a superbill for out-of-network claims and accept HSA and FSA.
No. Please arrange a ride home before your appointment.

We’ve Received Your Appointment Request

Thank you for choosing Wellness Clinic. Our specialist care team will contact you within the next 12 hours to confirm your appointment and answer any questions youmay have.

Need immediate assistance?

Our medical desk is available now.

Bookings information

Thanks for reaching out

our team will review your message and contact your shortly. we look forward to supporting your wellness journey

We’ve Sent Your $100 Coupon

Check your phone or email to receive your unique coupon code. You’ll need it when booking your first appointment.